While Annotation Studio is primarily intended for pedagogical use, its innovative and simplistic design requires no special training, thereby making it a valuable tool beyond the classroom.

Scholars can use Annotation Studio to easily organize and annotate large collections of texts, enabling them to maintain their research in a single and easily searchable interface.

Librarian, archivists and other museum professionals can use Annotation Studio to display significant texts from their collections or create digital archives, and then invite visitors to annotate and tag these texts.

Enthusiasts, including reading groups, can use Annotation Studio to share their personal responses with the world, creating new digital communities.